diff --git a/.github/workflows/main.yml b/.github/workflows/main.yml
index 53c0934ae..76c7a0d13 100644
--- a/.github/workflows/main.yml
+++ b/.github/workflows/main.yml
@@ -53,7 +53,7 @@ jobs:
       - name: Setup .NET
         uses: actions/setup-dotnet@v5
         with:
-          dotnet-version: '8.0.x'
+          dotnet-version: '10.0.x'
 
       - name: Set up Python ${{ matrix.python }}
         uses: astral-sh/setup-uv@v7
@@ -77,7 +77,7 @@ jobs:
           MONO_THREADS_SUSPEND: preemptive # https://github.com/mono/mono/issues/21466
 
       - name: Embedding tests (.NET Core)
-        run: dotnet test --runtime any-${{ matrix.os.platform }} --framework net8.0 --logger "console;verbosity=detailed" src/embed_tests/
+        run: dotnet test --runtime any-${{ matrix.os.platform }} --framework net10.0 --logger "console;verbosity=detailed" src/embed_tests/
         if: always()
 
       - name: Python Tests (Mono)
diff --git a/src/embed_tests/Python.EmbeddingTest.csproj b/src/embed_tests/Python.EmbeddingTest.csproj
index 28076120a..b3e7fe86e 100644
--- a/src/embed_tests/Python.EmbeddingTest.csproj
+++ b/src/embed_tests/Python.EmbeddingTest.csproj
@@ -1,7 +1,7 @@
 <Project Sdk="Microsoft.NET.Sdk">
 
   <PropertyGroup>
-    <TargetFrameworks>net472;net8.0</TargetFrameworks>
+    <TargetFrameworks>net472;net10.0</TargetFrameworks>
     <AssemblyOriginatorKeyFile>..\pythonnet.snk</AssemblyOriginatorKeyFile>
     <SignAssembly>true</SignAssembly>
   </PropertyGroup>
diff --git a/src/python_tests_runner/Python.PythonTestsRunner.csproj b/src/python_tests_runner/Python.PythonTestsRunner.csproj
index 5fc55d158..80e8c0071 100644
--- a/src/python_tests_runner/Python.PythonTestsRunner.csproj
+++ b/src/python_tests_runner/Python.PythonTestsRunner.csproj
@@ -1,7 +1,7 @@
 <Project Sdk="Microsoft.NET.Sdk">
 
   <PropertyGroup>
-    <TargetFrameworks>net472;net8.0</TargetFrameworks>
+    <TargetFrameworks>net472;net10.0</TargetFrameworks>
   </PropertyGroup>
 
   <ItemGroup>
diff --git a/src/runtime/AssemblyManager.cs b/src/runtime/AssemblyManager.cs
index 82658bf50..dcc5aa2f0 100644
--- a/src/runtime/AssemblyManager.cs
+++ b/src/runtime/AssemblyManager.cs
@@ -123,6 +123,11 @@ private static void AssemblyLoadHandler(object ob, AssemblyLoadEventArgs args)
 
         internal static AssemblyName? TryParseAssemblyName(string name)
         {
+            // workaround for https://github.com/dotnet/runtime/issues/123951
+            if (name.IndexOfAny(new[] { Path.DirectorySeparatorChar, Path.AltDirectorySeparatorChar }) >= 0)
+            {
+                return null;
+            }
             try
             {
                 return new AssemblyName(name);
diff --git a/src/testing/Python.Test.csproj b/src/testing/Python.Test.csproj
index b7ba6cd4e..c2455b1a5 100644
--- a/src/testing/Python.Test.csproj
+++ b/src/testing/Python.Test.csproj
@@ -1,6 +1,6 @@
 <Project Sdk="Microsoft.NET.Sdk">
   <PropertyGroup>
-    <TargetFrameworks>netstandard2.0;net8.0</TargetFrameworks>
+    <TargetFrameworks>netstandard2.0;net10.0</TargetFrameworks>
     <AllowUnsafeBlocks>true</AllowUnsafeBlocks>
     <GenerateRuntimeConfigurationFiles>true</GenerateRuntimeConfigurationFiles>
     <AssemblyOriginatorKeyFile>..\pythonnet.snk</AssemblyOriginatorKeyFile>